STO-Activities: (no title)
Activity title:
Treatment Challenges with CBRN Combined Injuries
Activity Reference:
HFM-378
Panel:
HFM
Security Classification:
PUBLIC RELEASE
Status:
Planning
Activity type:
RSM
Start date:
2024-01-15T00:00:00Z
Actual End date:
2026-01-14T00:00:00Z
Keywords:
CBRN injuries, CBRN medical countermeasures Multi Domain Operations, combat casualty care, Combined injuries
Background:
Future military operations are expected to be characterized by operations in austere environments, and mass casualty events, including from chemical, biological, radiological, and nuclear (CBRN) attacks. It is expected that especially CBRN incidents may involve polytrauma, such as blunt or penetrating injuries, burns, concussion, and traumatic hemorrhage. Complex Multi-Domain Operations (MDO) requires mastery across all domains of land, sea, air, space, and cyberspace. Challenges in mastering control of all domains is likely to result in delays in evacuating casualties beyond the “golden hour” and require greater emphasis on prolonged care of complex injuries. CBRN combined injuries add complexity to sustaining and evacuating injured personnel. Historically, there have been unconnected medical care guidelines for conventional polytrauma injuries (e.g., with hemorrhage, trauma, burns) and CBRN exposures with combined injuries. Military medical operations in MDO must be agile and synchronized to respond to injuries caused by unconventional weapons, novel operational environments, surges in casualty rates, and unexpected complications. This proposed initiative will support identification of capability gaps in medical management of conventional polytrauma in combination with CBRN injuries. This will lead to optimizing the efficacy and efficiency of approved therapies as well as novel, emerging interventions within NATO.
Objectives:
The primary objective is to identify research gaps and information needs to diagnosis and treat combined injuries, or CBRN polytrauma, defined as, chemical, biological, radiological, or nuclear exposure combine with one or more other traumatic injury(ies) such as traumatic brain injury, burns, blast wave, blunt or penetrating force. It is important to note that this definition is a working definition without consensus, and another focus of this RSM will be to standardize a definition of combined injury. The focus will be on identifying these research gaps and information needs for combined injuries that are relevant in an MDO environment with options to provide treatment near the point-of-injury, and address prolonged care in austere environments. Consideration will be given to standardizing practices across organizations, refining existing treatment protocols on polytrauma, updating Clinical Practice Guidelines on battlefield medicine, and identifying potential pharmaceutical approaches, including repurposing existing drugs, to treat combined injuries.
Topics:
Chemical, biological, radiological and nuclear (CBRN) injuries, models, and medical countermeasures, Polytrauma injuries, models, and medical countermeasures, Blast injuries, models, and medical countermeasures, Burn injuries, models, and medical countermeasures, Pathophysiology, Pharmacology, Toxicology, Clinical Practice Guidelines. Some essential questions to be answered:- What is the definition of combined injury? - What are current treatment protocols/CPGs for trauma injuries involving CBRN injury/exposure?- What do we need to realize these diagnostic and treatment strategies in an MDO environment? - What do we not know about the pathophysiology of combined CBRN? - How do we most efficiently inform these knowledge gaps?
Contact:
Open2Partners:
Title:
Created at 01/12/2023 15:00 by System Account
Last modified at 16/05/2024 13:00 by System Account
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